research published 2025-01-01 · by Lee YH, Shih PC, Su ST, Wei JC

International journal of rheumatic diseases · 2025 Jan

PubMed #39835510

Abstract

Chronic inflammation is a major characteristic of ankylosing spondylitis (AS) and is closely related to the mechanisms of cancer development. Persistent inflammatory responses can lead to DNA damage, gene mutations, and abnormal cell proliferation, all of which may increase the risk of cancer. We also explore the use of biologic therapy of AS and their potential cancer risks.

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