Possible SAMe-induced mania

Abstract

This paper describes a patient who presented with mania with psychotic features in the context of concomitant use of S-adenosyl-L-methionine (SAMe) and selective serotonin reuptake inhibitor (SSRI). The aim of this case report is to provide medical practitioners with a greater awareness of the possibility of a psychotic episode and/or mania manifesting with concurrent use of SAMe and SSRI.

Neurotransmitters

• Dopamine
• Norepinephrine (Noradrenaline)
• Serotonin (5-HT)

Related

• L-Methionine
• SAM-e (S-Adenosylmethionine)