IGF-1 LR3
A modified, long-acting form of insulin-like growth factor 1 — the anabolic mediator downstream of growth hormone — used to promote muscle growth and recovery. Not approved for human use.
Benefits
Why it is abused: promoted for muscle hyperplasia, recovery, and nutrient partitioning. Human evidence is essentially absent.
Risks
Hypoglycemia, concerns about organ/tissue overgrowth, and a theoretical cancer-promotion risk; unregulated purity. Banned in sport.
Informational only — not medical advice.
Body systems
Hormones
Research (4)
- Insulin and Insulin Resistance in Alzheimer's Disease Sędzikowska et al. (2021) PubMed ↗
- Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy Yoshida et al. (2020) PubMed ↗
- The role of hormones in muscle hypertrophy Fink et al. (2018) PubMed ↗
- Hormonal responses and adaptations to resistance exercise and training Kraemer et al. (2005) PubMed ↗
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