Ipamorelin
A selective growth-hormone-releasing peptide (a ghrelin-receptor agonist / GHRP) used to stimulate the body’s own growth-hormone pulses for recovery, body composition, and sleep. Not an approved drug.
Benefits
Why it is used: promoted for higher GH/IGF-1, better recovery, fat loss, and deeper sleep, with less hunger, cortisol, and prolactin effect than older GHRPs. Claims rest largely on early/animal data.
Risks
Research-grade and unapproved, with limited human safety data; possible water retention, tingling/numbness, raised blood sugar, and injection-site reactions. Purity is unregulated and it is banned in sport.
Informational only — not medical advice.
Body systems
Hormones
Research (4)
- Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians Mayfield et al. (2026) PubMed ↗
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions Rahman et al. (2026) PubMed ↗
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults Teichman et al. (2006) PubMed ↗
- Ipamorelin, the first selective growth hormone secretagogue Raun et al. (1998) PubMed ↗
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