Vitamin B12
Vitamin B12 is essential for nerve function, DNA synthesis, and neurotransmitter metabolism, and deficiency can cause fatigue, neuropathy, and cognitive or mood changes that supplementation reverses. In people who are not deficient, however, extra B12 has not been shown to boost energy, mood, or cognition. Deficiency is common in older adults, vegans, and those on certain medications.
Too little may be associated with
Deficiency: fatigue, neuropathy, cognitive and mood decline.
Too much may be associated with
Excess generally excreted; usually safe.
Informational only — not medical advice.
Neurotransmitters
Related
Research (13)
- Peripheral Neuropathy: A Review Mauermann et al. (2026)
- Folate Deficiency-Induced Pseudo-Thrombotic Microangiopathy Allemand et al. (2026)
- [Nutrition in improving sleep quality and fighting insomnia] Ortega et al. (2025)
- Vitamin B12 and Autism Spectrum Disorder: A Review of Current Evidence Zwierz et al. (2025)
- Vitamin B12 Deficiency: An Under-Addressed Community Health Problem Dhochak et al. (2025)
- Mechanistic Insights into the Link between Gut Dysbiosis and Major Depression: An Extensive Review Sonali et al. (2022)
- Late Life Vitamin B12 Deficiency Zik (2019)
- Investigating vitamin B12 deficiency Sukumar et al. (2019)
- Distal Symmetric Polyneuropathy: A Review Callaghan et al. (2015)
- Vitamin B12 deficiency Hunt et al. (2014)
- Vitamin B12 deficiency Abboud et al. (2013)
- Vitamin B12 deficiency Stabler (2013)
- Clinical practice. Vitamin B12 deficiency Stabler (2013)
Links
Community
Log in to rate and share your notes.
No contributions yet.