Cortisol
The body's primary glucocorticoid stress hormone, released on the HPA axis. It mobilizes glucose, sharpens alertness, and modulates immune and inflammatory responses; it follows a daily rhythm, peaking in the morning.
Too little may be associated with
Fatigue, low blood pressure, salt craving, and poor stress tolerance (as in adrenal insufficiency / Addison’s disease).
Too much may be associated with
Weight gain, high blood sugar and pressure, muscle loss, thinning skin, anxiety and poor sleep (as in Cushing’s syndrome or chronic stress).
Informational only — not medical advice.
Organ systems
Stimuli that influence it
Substances
Behaviors
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